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APC Resistance

eDH Procedure Code(s)

LAB2165 Thrombosis/Antiphospholipid Screen
LAB2169 Thrombosis/Antiphospholipid Panel —LAB ONLY

Test Information

If low APC Resistance is found, the Lavender tube is sent to Molecular Genetics for confirmation by the Factor V DNA mutation test.

Order Questions

LAB2165 Thrombosis/Antiphospholipid Screen
  • Please Select desired testing (Select one)
  • Does the patient have a history of thrombosis?
  • Is there a FAMILY history of thrombosis (e.g. blood clots in first-degree relatives)?
  • Is Patient Pregnant?
  • Is Patient on Warfarin?
  • Is Patient on Direct Oral Anticoagulant (DOAC)?
  • Please provide reason for testing -

Collection Information

1.8 mL Sodium Citrate tube filled to the line
OR
2.7 mL Sodium Citrate tube filled to the line
AND
2.0 mL EDTA tube
Blue top tubes must be filled within 10% of stated volume. A discard tube must be used if a citrate tube is to be drawn using a winged blood collection set. It is important to remove air from the blood collection set to ensure the proper blood volume is obtained in the coag tube.
If the patient has a known hematocrit >55%, please contact the coagulation lab for an adjusted collection tube before drawing the blood.

Specimen Information

Specimen Type Specimen Source Acceptable Containers Minimum Test Volume (mL)
Blood Blood, Venous BluCit-F 1.0
Blood Blood, Venous OrgCit-F  
Blood Blood, Venous Adjusted-F 1.0

Shipping and Handling

Processing Instructions: Double spin, separate, and freeze plasma. Freeze red cells in separate tube
Lavender top: send whole blood, Refrigerated.

Transport Temperature: Frozen AND refrigerated.
Transport Instructions: N/A

Specimen Stability Unprocessed
Unprocessed: 4 Hours
Specimen Stability Post Processing
Ambient: 4 hours
Refrigerated: N/A
Frozen: 2 weeks

Test Components

Component LOINC Code
ACTIVATED PROTEIN C RESISTANCE 13590-5

Turnaround Time (TAT)

8 Days

CPT Code(s)

85307

Performing Lab Section

Coagulation

Performing Lab(s)

Dartmouth Hitchcock Medical Center Laboratory (MHMH)