Thrombosis Screen
eD-H Order Code
LAB3421
Order Set Components
PT
PTT
Fibrinogen
Thrombin
Time
Platelet
Count
Silica
Clotting Time
dRVVT
Cardiolipin
Antibody Screen
Homocysteine
Total, Plasma
Beta 2
Glycoprotein I
Specimen Transport Temperature
Sodium Citrate (Blue Top) Tubes: Double spin, separate, and freeze
Lavender EDTA tubes: Ambient
Gold SST Tubes: Refrigerate
Green Lithium Heparin Tube: spin within 1 hour, refrigerate, no need to pour off plasma if gel barrier is present
Additional Specimen Instructions
2.7 mL Sodium Citrate tube filled to the line
5.0 mL Gold SST
2.0 mL EDTA Lavender tube
4.5 mL Green LIHEP PST tube
Collect FOUR 2.7 mL blue top tubes
Note: All Specimen must be collected
Blue top tubes must be filled within 10% of stated volume. A discard tube must be used if a citrate tube is to be drawn using a winged blood collection set. It is important to remove air from the blood collection set to ensure the proper blood volume is obtained in the coag tube.
If the patient has a known hematocrit >55%, please contact the coagulation lab for an adjusted collection tube before drawing the blood.
Run platelet count (EDTA) and send result. If not run, send EDTA tube at room temp less than 24 hours old (refrigerated up to 36 hours)
Double spin, separate, freeze plasma from coag (blue) tubes
Refrigerate red cells from a lavender EDTA tube in a seperate tube if platelet count is completed. If EDTA tube is unavailable, red cells from the sodium citrate (blue) tube may be used
Refrigerate SST tube for ACA
Green Lithium Heparin Tube: spin within one hour, refrigerate, no need to pour off plasma if gel barrier is present.
If sending a Thrombosis Screen from outside of the DH-H network please complete the top portion of the Thrombosis Screen Worksheet and include it with the specimen. A link to the worksheet can be found under the Resources section on this page.
Additional Testing Information
The thrombosis screen is an interactive algorithm intended to initially draw all specimen that might be required for evaluation of a suspected hyper-coaguable state (thrombophilia). Initial screening testing will include a platelet count, prothrombin time (PT), partial thromboplastin time (PTT), fibrinogen, and thrombin time. Based on clinical information, history and medications, additional testing will be completed.
Tests that may be included are: activated protein C (APC) resistance screening (with factor V leiden mutation if abnormal), antithrombin (AT3), protein C, protein S, lupus anticoagulant panel, anticardiolipin antibodies, beta-2-glycoprotein-1 antibodies, homocysteine, and prothrombin G20210A mutation.
Results will be summarized in a Pathologists interpretive report, available in eD-H.
CPT(s)
86147 ; 83090 ; 86146 ; 85049 ; 85610 ; 85730 ; 85670 ; 85384 ; 85049 ; 85384 ; 85610 ; 85730 ; 85670 ; 85613 ; 85730 ;
Performing Lab Section
Hematology