Alpha-Galactosidase, Leukocytes
Ordering Guidance
If testing is needed for assessment of meat or meat-derived product allergy, order either ALGAL / Galactose-Alpha-1,3-Galactose (Alpha-Gal), IgE, Serum or APGAL / Galactose-Alpha-1,3-Galactose (Alpha-Gal) Mammalian Meat Allergy Profile, Serum.
Carrier detection using enzyme levels is unreliable for female patients as results may be within the normal values. Order GLA / Fabry Disease, GLA Gene Sequencing with Deletion/Duplication, Varies for testing carrier status.
Shipping Instructions
For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerated within 6 days of collection to be stabilized. Pre-analytical processing is performed Monday through Friday and Sunday. This test may be canceled if specimens are outside of stability when processing occurs. Collect and package specimens for arrival on days when processing is performed.
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Yellow top (ACD solution A) or lavender top (EDTA)
Specimen Volume: 6 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602)
3. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.
Special Instructions
Specimen Type
Whole Blood ACDSpecimen Minimum Volume
4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood ACD | Refrigerated (preferred) | 6 days |
| Ambient | 6 days |
Reference Values
≥10.32 nmol/hour/mg protein
An interpretative report will be provided.
Note: Results from this assay do not reflect carrier status because of individual variation of alpha-galactosidase enzyme levels.
Day(s) Performed
Preanalytical processing: Monday through Friday, Sunday
Assay performed: Monday, Thursday
Report Available
2 to 5 daysSpecimen Retention Time
White blood cell homogenate: 1 monthPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82657
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AGAW | Alpha-Galactosidase, Leukocytes | 24049-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 606261 | Alpha-Galactosidase, Leukocytes | 24049-9 |
| 606262 | Interpretation | 59462-2 |
| 606263 | Reviewed By | 18771-6 |