Botulism Toxin
eD-H Order Code
Miscellaneous Lab Request (LAB3517)
Specimen Collection Information
Acceptable specimens: Review with NHPHL/CDC.
CDC Test Directory: https://www.cdc.gov/laboratory/specimen-submission/list.html
Special paper requisition (CDC Form 50.34) must be completed by ordering provider and submitted to the laboratory with the specimen.
CDC accepts specimens from suspected botulism cases (no rule-out testing). CDC does not provide microbial identification or toxin testing on specimens not associated with clinical botulism cases.
Foodborne botulism: pre-antitoxin serum (without anti-coagulant), stool, enema (with sterile non-bacteriostatic water), food. Although not ideal, gastric contents may also be submitted.
Wound botulism: pre-antitoxin serum (without anti-coagulant), debrided tissue, swab from wounds, stool (only if foodborne is also suspected).
Infant botulism: stool, enema (with sterile non-bacteriostatic water), rectal swabs. Potential sources (honey or opened powdered formula) may also be submitted.
Unopened commercial products are accepted only with permission from FDA or USDA.
Specimen Transport Temperature
Refrigerate or Frozen- dependant on direction from NHPHL/CDC
Specimen Stability
Hold specimen until the physician contacts the CDC; refrigerate 2-8ºC.
Stool- 48 hours refrigerated or frozen
Specimen are sent directly to the CDC or via NH State lab per CDC direction/specifications.
Day(s) Performed
Specimens are sent to NHPHL/CDC Monday-Thursday by Microbiology Laboratory staff.
Fridays, Weekends and Holidays: Contact Microbiology Laboratory before collecting specimen
Performing Lab Section
Microbiology, Testing performed by CDC