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Endomysial Antibodies, IgA, Serum

Additional Codes

Order in eDH using Miscellaneous Lab Request (LAB3715).

This test requires Pathologist approval and can only be ordered in Cerner Millennium by Mailouts Dept (xEndomysial IgA-Mayo) .

Endomysial Antibodies (IgA) is not as sensitive as TTG IgA for celiac disease screening.  It should not be used as a first line test for screening. A negative result for endomysial antibodies does not exclude the diagnosis of dermatitis herpetiformis or celiac disease. Patients with mild gluten-sensitive enteropathy may also have a negative result.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Advisory Information


Cascade testing is recommended for celiac disease. Cascade testing ensures that testing proceeds in an algorithmic fashion. The following cascades are available; select the appropriate one for your specific patient situation.

-For complete testing including human leukocyte antigen (HLA) DQ, order CDCOM / Celiac Disease Comprehensive Cascade, Serum and Whole Blood

-For complete testing excluding HLA DQ, order CDSP / Celiac Disease Serology Cascade, Serum

-For patients already adhering to a gluten-free diet, order CDGF / Celiac Disease Gluten-Free Cascade, Serum and Whole Blood

 

To order individual tests, see Celiac Disease Diagnostic Testing Algorithm in Special Instructions.



Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red Top

Specimen Volume: 2 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reference Values

Negative in normal individuals; also negative in dermatitis herpetiformis or celiac disease patients adhering to gluten-free diet.

Day(s) and Time(s) Performed

Monday through Friday; 7 a.m.-5 p.m.

CPT Code Information

86255-screen

86256-titer (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EMA Endomysial Abs, S (IgA) 46126-9

 

Result ID Test Result Name Result LOINC Value
9360 Endomysial Ab 46126-9

Analytic Time

2 days

Specimen Retention Time

14 days

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
EMAT EMA Titer, S (IgA) No No

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.