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Infliximab Quantitation with Reflex to Antibodies to Infliximab, Serum

Additional Codes

LAB4023

Profile Information

Test ID Reporting Name Available Separately Always Performed
INFX Infliximab, S No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
INXAB Infliximab Ab, S No No

Specimen Type

Serum Red


Specimen Required


Patient Preparation:

1. Draw blood immediately before next scheduled dose (trough specimen).

2. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Container/Tube: Red top (serum ger/SST are not acceptable)

Specimen Volume: 1 mL

Collection Instructions: Centrifuge within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Frozen (preferred) 28 days
  Refrigerated  28 days

Reference Values

INFLIXIMAB QUANTITATION:

Limit of quantitation is 1.0 mcg/mL. Therapeutic ranges are disease specific.

 

Pediatric reference ranges are not established.

 

INFLIXIMAB ANTIBODIES

Absence of antibodies to infliximab (ATI) is defined as <50 U/mL

Presence of ATI is reported as positive when concentrations are ≥50 U/mL

Analytic Time

3 days

Specimen Retention Time

2 weeks

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80230

82397-(if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
INFXR Infliximab QN with Reflex to Ab, S 39803-2

 

Result ID Test Result Name Result LOINC Value
63000 Infliximab, S 39803-2
36847 Interpretation 59462-2

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.

Day(s) and Time(s) Performed

INFX: Monday, Wednesday, Thursday; 4 p.m.

INXAB: Monday, Wednesday, Friday; 8 a.m.