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Porphyrins, Quantitative, 24 Hour, Urine

Important Note

This test (Porphyrins, Quantitative, 24hr Urine) can only be order in eDH using Miscellaneous Lab Request (LAB3715). This test requires Pathologist approval and can only be ordered in Cerner Millennium by the Mailout Dept (xU24 Porphyrins Qnt).

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


This 24-hour urine test should be ordered when the specimen will not reach Mayo Clinic Laboratories (MCL) within 72 hours. If the specimen will reach MCL within 72 hours, order PQNRU / Porphyrins, Quantitative, Random, Urine.



Shipping Instructions


Ship specimen in amber container to protect from light.



Necessary Information


1. 24-Hour volume (in milliliters) is required.

2. Patient's sex is required.

3. Collection date and time should be documented upon completion of the 24-hour collection.

4. Include a list of medications the patient is currently taking.



Specimen Required


Patient Preparation: Patient should not consume any alcohol for the 24 hours before, as well as during, specimen collection.

Supplies:

-Urine Container - Amber, 60-mL (T596)

-Sodium Carbonate, 5 gram (T272)

Container/Tube: Amber, 60-mL urine container

Specimen Volume: 20 to 50 mL

Collection Instructions:

1. Add 5 g of sodium carbonate as preservative at start of collection. This preservative is intended to achieve a pH above 7. Do not substitute sodium bicarbonate for sodium carbonate.

2. Collect a 24-hour urine specimen.

3. The container should be refrigerated and protected from light as much as possible during collection.

4. Record volume and duration. An aliquot should be frozen when collection is complete.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

15 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen 7 days LIGHT PROTECTED

Reference Values

Uroporphyrins (Octacarboxyl):

≤30 nmol/24 h

 

Heptacarboxylporphyrins:

≤9 nmol/24 h

 

Hexacarboxylporphyrins:

≤8 nmol/24 h

 

Pentacarboxyporphyrins:

≤10 nmol/24 h

 

Copropprphyrins (Tetracboxyl)

Males: ≤230 nmol/24 h

Females: ≤168 nmol/24 h

 

Porphobilinogen:

≤2.2 mcmol/24 h

Day(s) Performed

Monday through Friday

CPT Code Information

84110-Porphobilinogen, quantitative

84120-Porphyrins, quantitation and fractionation

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PQNU Porphyrins, QN, U 43116-3

 

Result ID Test Result Name Result LOINC Value
TM3 Collection Duration 13362-9
VL1 Urine Volume 3167-4
29357 Uroporphyrin, Octa 15096-1
29358 Heptacarboxylporphyrins 25434-2
29359 Hexacarboxylporphyrins 25438-3
29360 Pentacarboxylporphyrins 25494-6
29361 Coproporphyrin, Tetra 15041-7
29362 Porphobilinogen 14882-5
23403 Interpretation 59462-2

Report Available

2 to 4 days

Specimen Retention Time

1 week