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HelpCerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid
Additional Codes
LAB555
Specimen Required
Both serum and spinal fluid are required.
-Spinal fluid must be obtained within 7 days of serum collection.
-Two individual serum samples are required.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: 2 Plastic vials
Specimen Volume: 2 mL in 2 plastic vials, each vial containing 1 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into 2 plastic vials.
Specimen Type: Spinal fluid
Container/Tube: Sterile vial
Preferred: Collection vial number 2
Specimen Volume: 1 mL
Collection Instructions: Label specimen as SFINC.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| SFINC | IgG Index, CSF | No | Yes |
| SFIGS | IgG, S | No | Yes |
| ALBS1 | Albumin, S | Yes, (order ALB) | Yes |
Specimen Type
CSFSerum
Specimen Minimum Volume
Serum: 1 mL in 2 plastic vials, each vial containing 0.5 mL; Spinal fluid: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 14 days | |
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 7 days |
Reference Values
CSF index: 0.00-0.70
CSF IgG: 0.0-8.1 mg/dL
CSF albumin: 0.0-27.0 mg/dL
Serum IgG
0-4 months: 100-334 mg/dL
5-8 months: 164-588 mg/dL
9-14 months: 246-904 mg/dL
15-23 months: 313-1,170 mg/dL
2-3 years: 295-1,156 mg/dL
4-6 years: 386-1,470 mg/dL
7-9 years: 462-1,682 mg/dL
10-12 years: 503-1,719 mg/dL
13-15 years: 509-1,580 mg/dL
16-17 years: 487-1,327 mg/dL
≥18 years: 767-1,590 mg/dL
Serum albumin
≥12 months: 3,500-5,000 mg/dL
Reference values have not been established for patients who are younger than 12 months.
CSF IgG/albumin: 0.00-0.21
Serum IgG/albumin: 0.0-0.4
CSF IgG synthesis rate: 0-12 mg/24 h
Albumin quotient: <14
Day(s) Performed
Monday through Friday
Report Available
2 to 5 daysSpecimen Retention Time
See Individual Test IDsPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82040
82042
82784 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SFIG | CSF IgG Index Profile | 14116-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| INDEX | IgG Index, CSF | 14117-6 |
| ALB_S | Albumin, S | 1751-7 |
| IGG_S | IgG, S | 2465-3 |
| AIGAS | IgG/Albumin, S | 6782-7 |
| IGG_C | IgG, CSF | 2464-6 |
| ALB_C | Albumin, CSF | 1746-7 |
| ALBQ | Albumin Quotient, CSF/Serum | 1756-6 |
| AIGAC | IgG/Albumin, CSF | 2470-3 |
| SRATE | Synthesis Rate, CSF | 14116-8 |